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Compliance · AU

Quality assurance for medical devices in Australia

In short

Medical device sponsors and manufacturers in Australia must maintain a quality management system that meets the Essential Principles and conformity assessment procedures under the Therapeutic Goods (Medical Devices) Regulations 2002. This guide covers the 10 core quality assurance obligations for devices entered in the ARTG.

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Who must comply

Coverage

Australian sponsors, manufacturers and notified bodies of medical devices — including in-vitro diagnostic devices, Class I to Class III devices, active implantable devices and software as a medical device.

Legal basis

Therapeutic Goods Act 1989 (Cth), particularly Chapter 4. Therapeutic Goods (Medical Devices) Regulations 2002, sch 1 (Essential Principles) and sch 3 (Conformity Assessment Procedures). ISO 13485 (harmonised QMS standard) and TGA Essential Principles guidance.

10 obligations

The obligations

1

Implement a compliant QMS

Maintain a quality management system (typically aligned with ISO 13485) that addresses design, production, distribution and post-market requirements across the product lifecycle.

Therapeutic Goods (Medical Devices) Regulations 2002 sch 3
2

Demonstrate the Essential Principles

Demonstrate that each device meets the 15 Essential Principles for safety and performance, with evidence documented in a technical file.

Therapeutic Goods (Medical Devices) Regulations 2002 sch 1
3

Classify devices correctly

Classify the device (Class I, Is, Im, IIa, IIb, III, AIMD or IVD class) using the rules in the Regulations, as this drives the conformity assessment pathway.

Therapeutic Goods (Medical Devices) Regulations 2002 sch 2
4

Use appropriate conformity assessment

Apply the correct conformity assessment procedure, including TGA or comparable overseas regulator certificates as evidence for ARTG inclusion.

Therapeutic Goods Act 1989 (Cth) s 41LB
5

Conduct design controls and risk management

Run design controls and risk management aligned with ISO 14971, with verification and validation records retained for each design change.

Therapeutic Goods (Medical Devices) Regulations 2002 sch 1 cl 2
6

Maintain a post-market surveillance plan

Operate a post-market surveillance plan that captures complaints, field performance data and periodic safety updates for regulator review.

Therapeutic Goods Act 1989 (Cth) s 41MP
7

Report adverse events to the TGA

Report device-related serious adverse events, near misses and trend notifications to the TGA within the mandated timeframes.

Therapeutic Goods Act 1989 (Cth) s 41MP; TGA reporting guidance
8

Control changes and variations

Notify the TGA of ARTG variations — including manufacturer, sponsor, intended use and significant design changes — before supply continues.

Therapeutic Goods Act 1989 (Cth) s 41FN
9

Manage unique device identification

Prepare for TGA Unique Device Identifier requirements for labelling and device registry submissions as they commence for each class.

TGA UDI framework; Therapeutic Goods Act 1989 (Cth)
10

Retain QMS records for the specified period

Retain QMS and technical file records for the life of the device plus the period specified in the Regulations, and make them available for TGA inspection.

Therapeutic Goods (Medical Devices) Regulations 2002 sch 3 cl 1.7
Penalties

What happens if you do not comply

Non-compliance can trigger TGA suspensions or cancellations of ARTG entries, conformity assessment certificate suspensions, civil penalties of up to approximately $1.565 million per contravention for individuals and $15.65 million for corporations, and criminal offences.

Reporting requirements

Sponsors must submit annual reports, adverse event reports, PMS reports, ARTG variation notifications and responses to TGA post-market reviews or audits.

Practical steps

What firms should do today

  • Map the QMS to ISO 13485 and the Essential Principles with a gap matrix
  • Maintain a per-device technical file and post-market surveillance plan
  • Run a quarterly management review covering complaints and CAPAs
  • Track ARTG variations through a controlled change register
  • Keep TGA Unique Device Identifier readiness on the roadmap
Use with Quillio

Compliance with Quillio

Quillio reviews supply, manufacturing and distribution agreements to align QMS responsibilities, change controls and post-market surveillance data flow with TGA obligations. See /resources/security.

This guide is general information about medical device quality assurance in Australia — not legal or regulatory advice. Sponsors should work with a specialist regulatory lawyer and QMS consultant.

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